Individual selection bronhorasshiryayuschimi funds
Select bronhorasshiryayuschimi drugs is dependent on the reaction of the bronchial tree in the pharmacological tests. If you have a high positive response to beta-2 agonists are the most acceptable is 3-4-one-time appointment of short-dose inhalers (berotek, salbutamol, Ventolin, and others) at regular intervals: this tactic allows the patient without waiting for asthma or wheezing to exercise their effective prevention. If, despite the 3-4-one-time reception of these drugs, difficulty in breathing or asthma still appears necessary to use drugs with a longer bronhorasshiryayuschimi action: a combination of beta-2 agonists with cholinolytics (salbutamol + atrovent, berodual, etc.) or long-term acting beta-2 agonists: selmeterol or formoterol. In the acute phase of the disease is often a good bronhorasshiryayuschy effect is achieved by a combination of selective sympathomimetic (beroteka, salbutamol) with combined preparations containing ephedrine or its analogs (for example, bronholitin or solutan). However, in these cases, treatment must take place under the supervision of a physician and does not exceed 2-3 weeks.
With little positive response to the selective sympathomimetics prescribers only to prevent bronhokonstriktornyh reactions to the inhalation of corticosteroids or INTAL, because even a minor breach of airway impairs their penetration, decreasing the effectiveness of anti-inflammatory and antiallergic actions. In addition, during the day bronchodilators may be appointed by situational – to relieve asthma attacks or wheezing. THUS TOTAL INHALATION SHOULD NOT EXCEED 4.5 doses per day (per Short DRUGS – BEROTEK, salbutamol). When breathing difficulties or seizures at night is most expedient for the night inhalation doses of 1.2 beroduala (or appropriate combinations of sympathomimetics cholinolytics). In case of failure of this attempt can try inhalation sympathomimetics and cholinolytics combined with additional methods for a night of prolonged theophylline (but only on prescription!). PATIENTS with no or lower rate of response to beta-2-STIMULANTS inappropriate to apply PREPARATIONS PROLONGED ACTION (salmeterol and formoterol), since their appointment, according to available data, can mask degradation.
In appointing bronhorasshiryayuschimi drugs the doctor must warn patients of the two extremes: when a good response to beta-2-stimulants – from the irregularity of their admission, and at bad reactions – from excessive use. Many patients and even some doctors there is an opinion as addiction to these drugs and their harmful when taken regularly. This myth was born during the rule of the theory of beta-blockade. Recent studies have found that the number of 3.4 doses per day of inhaled, these products are absolutely harmless, and in their application at the recommended doses of so-called desensitization effect – reducing the sensitivity to beta-2-stimulants (rather far-fetched than what has been proved correct) — not develop. The benefit also from systematic inhalation is that by maintaining airway at an optimal level, they provide a normal bronchial drainage, thus preventing the progression of obstruction and a worsening of the disease.
And the doctor and the patient must remember the following: if, when applying bronhorasshiryayuschimi AEROSOL A decrease their effectiveness or increased demands of Inhalation, This means that the bronchial tree Grows obturation inflammatory swelling or mucus. In such a situation it is necessary to take emergency measures.
