Composition and the form. Active substance – clomipramine hydrochloride. Buy anafranil in drops, pills, tablets, ointment, solution for injection in ampoules.

Pharmacological action. Potent tricyclic antidepressant; timolepticheskoe has a pronounced effect, reduces agitation. Has adrenolytic and antihistaminic effects of online anafranil. Almost does not cause sedation and fatigue.

Indications. Depressive syndrome of various etiologies: an endogenous, reactive, neurotic, organic, larvirovanny, involutional, with psychopathy, schizophrenia, chronic pain and somatic diseases. Dysthymic states in psychopathic disorders in children and adolescents. Obsessive-compulsive disorder and phobias. Cataplexy in narcolepsy. Nocturnal enuresis success with anafranil (aged 5 years and after exclusion of organic causes of disorders).

Dosage regimen. Set individually. Depression, phobias – 25 mg 2-3 times a day. During the first week gradually increase the dose to 50 mg 2-3 times. After a pronounced improvement of the patient is transferred to the maintenance dose – 25 mg 2-3 times. V / m is introduced to 25-50 mg per day, increase the dose every day for up to 25 mg daily dose of 100-150 mg. V / injected into infusion over 1.5-3 h 1 times a day for 50-75 mg in 250-500 ml of isotonic glucose or sodium chloride. After 3-5 days of infusion therapy the patient is transferred to the reception of the  anafranil generic.

In chronic pain-tion dose is 10 to 150 mg / day. In elderly patients initial daily dose of 10 mg, gradually over 10 days increase the dose to 30-50 mg / day. For children starting dose of 10 mg / day. Within 10 days increase the dose in children aged 5-7 years to 20 mg, 8-14 years – up to 20-50 mg, the age of 14 to 50 mg / day and above.

Side effects anafranil drug. At the beginning of treatment – dry mouth, excessive sweating, fine tremor, dizziness, accommodation disturbances and urination, postural hypotension, confusion. Allergic skin reactions. In high doses – conduction disorders, arrhythmia, insomnia, mental confusion, increased fear. Seldom – liver dysfunction, hyperpyrexia, seizures, agranulocytosis.

Contraindications. Increased sensitivity to tricyclic antidepressants in the group dibenzazepina. Pregnancy, lactation anafranil without prescription.

Cautions. During treatment, medication should avoid alcohol. When poisoning drug shows gastric lavage, with severe anticholinergic symptoms of central nervous system – 0,5-2 mg physostigmine / m or /.

Manufacturers. Anafranil (Anafranil) CIBA-GEIGY, Switzerland; Gidifen (Gidifen) AWD, Germany; Klofranil (Klofranil) SUN PHARMACEUTICAL, India.