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Nolvadex
Latin name: Nolvadex
Pharmacological group: Antineoplastic hormonal antagonists and hormones. Estrogens, gestagens, and their homologs and antagonists
Nosological classification (ICD-10): C43 Malignant melanoma of the skin. C49 Malignant neoplasm of other types of connective and soft tissue. C50 Malignant neoplasm of breast cancer. C54 Malignant neoplasm of corpus uteri. C54.1 endometrium. C61 Malignant neoplasm of the prostate. C64 Malignant neoplasm kidney, except renal pelvis. C75.1 pituitary. D35.2 pituitary. D44.3 pituitary. N46 Male infertility. N97 Female infertility
Pharmacological action
Substance (INN) Tamoxifen (Tamoxifen)
Application: Breast cancer, especially in women after menopause, endometrial cancer, kidney, soft tissue sarcoma, anovulatory infertility, oligospermia, pituitary tumor.
Contraindications: Pregnancy, thrombophlebitis.
Restrictions apply to: leukopenia, thrombocytopenia, hypercalcemia.
Side effects: gastrointestinal disorders (anorexia, nausea, vomiting), dizziness, skin rash, hypercalcemia, thrombocytopenia, moderate metrorrhagia, thrombosis, very rarely – increased body temperature, extremely rare – clouding of the cornea, degeneration of the retina.
Interaction: Cytostatics increase the risk of thrombotic events. Can be successfully used in combination with progestin.
Dosing and dose: Inside, in breast cancer, endometrial, kidney – 10-20 mg 2-3 times per day, per course – 2,4-9,6 g; treatment is carried out before the signs of the regression process and during the next 1-2 months. In anovulatory infertility appoint 10 mg 2 times a day for 4 days, starting with 2 days of menstruation, then the dose can be increased to 20 mg, and then – 40 mg. In the event of termination of office of milk after childbirth – 10 mg 4 times a day for 5 days. When oligospermia – 10 mg 2 times a day.
Precautions: In the course of treatment is necessary to monitor the number of leukocytes, platelets, calcium level, indicators of blood coagulation.
Cautions: Not effective in the treatment of patients with metastases (particularly liver).
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For treatment of breast cancer in women in the early stages of use order nolvadex. This is a non-steroidal drug that reduces the production of the female hormone estrogen in the body, thereby reducing the risk of breast cancer.
Despite the fact that Nolvadex is designed for the act of women, he found the use of men. As is well known in the male body also occurs in estrogen in small amounts. Male athletes who are building muscle mass using buy nolvadex and clomid to reduce the level of the female hormone in combination with other drugs that increase the level of the male hormone testosterone.
Nolvadex is released strictly on prescription, and should be taken under strict medical supervision. Do not take Nolvadex without consulting a doctor because it could be dangerous to your health.
Buy nolvadex has many side effects. In the best case, you may encounter with allergic reactions such as hives, difficulty breathing and swelling. There are more serious side effects, which may cause Nolvadex. They include sudden numbness, headache, blurred vision and trdnosti speech, chest pain, cough with blood, swelling in the legs, irregular menstrual periods, unusual vaginal bleeding. In the event of any of these symptoms you should seek medical help.
