Florinef weight loss diuretic
Side effects in overdose.
Contraindications and limitations to the application.
FLORINEF (Florinef) Fludrokortizon *
Pharmacological action
Making up the deficit of hormones of the adrenal cortex participates in metabolism, Wh mineral and carbohydrate, inhibits the sodium ions and promotes the excretion of potassium
INDICATIONS
Replacement therapy for severe insufficiency of the adrenal cortex, in particular, with Addison’s disease, adrenogenital syndrome with loss of salts
CONTRAINDICATIONS
Mental illness history, herpes viral infections, amebiasis, systemic mycosis, stomach ulcer and duodenal ulcer, polio, osteoporosis, before and after immunization
Restrictions apply
During pregnancy (especially in the I trimester) is appointed only if absolutely indicated lactating women should abandon breastfeeding
SIDE EFFECTS
When using high doses – the oppression of pituitary function (gipofi-Sarnen ACTH secretion), decreased activity of the thymus and education Cortizo-la, the activation of gluconeogenesis, a negative nitrogen balance, growth inhibition in children subkapsulyarnye cataract, increased intraocular pressure, petechiae, erosive and ulcerative lesions tract, menstrual irregularities, edema, increased blood pressure, aseptic necrosis of bone
PRECAUTIONS
With care appoint at a history of peptic ulcer disease, myasthenia gravis, diverticulitis, recent intestinal anastomosis, and the inclination to. Thrombosis and embolism, metastatic carcinoma, tuberculosis (you can activate the process), diabetes (probably decompensation) to avoid edema and increasing blood pressure patients advised to observe a diet restriction of consumption of salt If you have any infections during therapy drug require immediate treatment with antibiotics or chemotherapy when long-term treatment should be regularly monitored the concentration of electrolytes and glucose in the blood serum
DOSAGE AND ADMINISTRATION
Inside, from 0.1 mg 3 times a week – up to 0.2 mg daily to patients with hypertension – at 0.05 mg per day is recommended given in combination with cortisone (6,25-25 mg / day) or hydrocortisone ( 5-20 mg / day), especially when replacement therapy
