Claritin coupon
Among the many allergy medications, few have proved equally effective and safe, that the time-tested and confirmed in clinical practice.
In pediatrics in choosing the treatment method, we first follow the principle of security. But often doctors and pharmacists do not think about the safety of treatment for each individual patient, including children.
We pediatricians are not as extensive choice of allergy, like allergists for the treatment of adults. In the appointment of antiallergic drug, like any other drug, you must take into account the presence of contraindications, concomitant diseases, the patient’s age, carried out simultaneously treatment with other medicines and much more.
It is well known that traditional antihistamines (I generation) have side effects that limit their use. Admission of children antihistamines with sedative effects, especially in long-term, negative impact on the mental and psychological development of children, violates the learning and remembering. This should be taken into account by imposing an anti-allergic therapy. Today, virtually no such children, who have pointed to only one disease, especially when it comes to allergies. Typically, there multiorgan pathology: diseases of the digestive tract, respiratory, nervous, urogenital system, etc., which significantly limits the possibility of using classical antihistamines.
Use in children most of the new antihistamines (akrivastin, Ebastine, fexofenadine) is limited to age (prescribed only for children older than 12 years), and therefore to treat the majority of our patients, they also can not be used.
Because some drugs II generation (terfenadine and astemizole), as well as some of their metabolites may have cardiotoxic effects, with the appointment of these drugs in high doses to take into account many factors, and observe a number of precautions (monitoring ECG during treatment).
Another selection criterion antiallergic drug – its effectiveness. Most antihistamines, usually affecting only one link of allergy – block H1-receptors and do not manifest biological effects of histamine. But allergies – is a complex process that involves many components. Consequently, more than a pathogenetic mechanisms, we can influence, the greater the effectiveness of treatment. Therefore, with the advent of drugs that act on various components of allergy, significantly expands the possibilities of therapy.
One of the few drugs that address the complex problem of allergies is Claritin (Loratadine). Throughout the world, he has proved the most effective and safe anti-allergic agent. According to the company IMS, in 1994, Claritin is the most nominated by the world anti-allergic drugs [9]. The fact is that along with the H1-blocking effect of Claritin allergy has some additional properties [10], which are very important in clinical practice because, first, to extend the therapeutic possibilities of the drug in the treatment of various allergic diseases, secondly, to avoid appointment of a large number of other drugs (Claritin has antihydropic and vasoconstrictor effects on the nasal mucosa, prevents spasm of the bronchi, has a membrane stabilizing effect, etc.). Claritin has proven its value in the complex treatment of concomitant allergic diseases such as bronchial asthma and allergic rhinitis, atopic dermatitis and bronchial asthma and others [7,10]. Its use allows you to quickly achieve remission and to prevent exacerbations of chronic allergic diseases, especially in children.
In pediatrics a significant role in choosing the antihistamine is the fact that the majority of allergy medications are not recommended for use more than 7-10 days, since more than a long reception of their effectiveness is reduced [7,10,11], and the risk of side effects increases. The cost of treatment Claritin comparable with that in the treatment of traditional antihistamines (Chloropyramine, clemastine, ketotifenom) despite the fact that the side effects associated with its use is very rare.
Because most of our patients have chronic pathologies requiring long-term treatment and prevention of anti-allergic drugs, given the above, we choose Claritin, which is highly effective and safe anti-allergic drug, which can be used in children from 1 year as a short course – in case of acute allergic diseases, as well and long-term – from 3 to 12 months in chronic or recurrent allergic diseases such as atopic dermatitis, allergic rhinitis, atopic asthma, urticaria, and others [7,10]. Claritin be taken orally 1 time a day regardless of meals. Children aged 1 to 2 years Claritin prescribed dose 2.5 mg (2.5 ml of syrup or 1 / 4 tablet), from 2 to 12 years – 5 mg (5 ml syrup or 1 / 2 tablets) 12 years of age and adults – 10 mg (10 ml of syrup or 1 tablet).
Claritin has virtually no contraindications to the use (except for hypersensitivity to the drug), rarely causes side effects, compatibility with other drugs, do not potentiate the action of alcohol. The drug can be used in children, adults, elderly patients.
Currently, there are new antihistamines, which are metabolites of drugs II generation, which may prove more effective, but to prove themselves safe and to confirm this reputation will take time and experience in their clinical application. Claritin is a long history of successful clinical use in more than 100 countries.
Appointing Claritin children, we are always confident in the success and safety of treatment.
So why are all the same Claritin?
Given the above, the following conclusions:
· Prove efficacy and safety of Claritin – the most widely used in the world antiallergic drug.
• In contrast to the I-generation antihistamines Claritin:
- Has the highest affinity for the H1-receptor (I-generation drugs – an average of about 30%) [6,11];
- Does not displace histamine from the connection with the H1-receptor;
- Does not cause dryness of the skin and mucous membranes;
- No negative effect on the function of the digestive tract;
- Blocking H1-receptors within 24 h (the duration of the drugs I generation – 2-4 h) [6,8].
· Along with the blockade of H1-receptor Claritin has additional effects, influencing other pathogenic mechanisms of allergy.
· Claritin additionally has vasoconstrictive and antihydropic effect on the mucous membrane of the nasal cavity, Moderate bronchodilators, antitussive effect, reduces bronchial hyperreactivity, which is particularly important when combined dermatological and respiratory allergies [6, 8, 10, 11].
· Claritin does not cause the development of tachyphylaxis during long-term prophylactic use [6, 10, 11].
· Claritin can be given simultaneously with other drugs, including antihistamines I generation.
· Rapid development of additional allergy effects, including membrane-stabilizing, the Claritin notes from the 5 th day course-taking (in the treatment ketotifenom – 4 th week of therapy) [8].
· Combination of H1-receptor blockade and other allergy effects allows for rapid development of clinical effect and replace the method using one of several drugs – Claritin.
